This series is manic. Think of the hyperactiveness of Azumanga Daioh's Tomoyo, coupled with the weirdness of FLCL and the ecchiness of Najica Blitz Tactics, and you're getting close. Not quite there yet, but close.
It's about a group of hoodlums from 'Panther Claw' who run amok in the city. A police inspector (a short-skirted woman, of course), assisted by hordes of ineffectual cannon fodder-but-always-smiling policemen tries to contain the mayhem, but in the end Cutie Honey (an android of some sort, out for revenge against those who killed the professor who created her) has to save the city from Golden Claw and her minions.
It's too manic for our tastes, anyway. But if you're not too heavily into plot and like hyperactive anime, you might want to give it a shot.